Orotic acid, anhydrous, ACS – CAS 65-86-1

 347.00

SKU: 65-86-1 Category:

Additional information

Weight 100 g
product name

Orotic acid, anhydrous, ACS

synonyms

2,6-Dihydroxypyrimidine-4-carboxylic acid,
6-Carboxy-2,4-dihydroxypyrimidine,
6-Carboxyuracil, Uracil-6-carboxylic acid

product origin

100% made in European Union (according to USP, EUP, ECHA-REACH)

purity grade

>99.99% (raw virgin matter, ultra-pure, sterilized)

use

lab. / tech. / bio-research / intermediate / industrial

product code

EA2294

C.A.S. number

65-86-1

MDL

MFCD00006027

EINECS

200-619-8

ID PubChem substance

24897967

empirical formula

C5H4N2O4 (Hill Notation)

formula weight

156.10

melting point

>300 °C (lit.)

solubility

slightly soluble in water

stability

stable under normal conditions

incompatible materials

bases, strong oxidizing agent, amines

identification (FTIR)

conforms

decomposition products

Nitrogen oxides (NOx);
Carbon monoxide (CO);
Carbon dioxide (CO2)

loss on drying

≤1.5% (200 °C / constant weight)

sensitivity & storage

ambient temperature

assay

>99.99%

appearance (color)

white

form

powder

applications

Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5?-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5?-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

note (1)

<span style="font-weight:700; color:red;"> this product is for research use only, is not to be used for therapeutic ; not intended for animal or human or diagnostic or therapeutic use , and cannot be sold to patients.</span>

note (2)

described price of the product is NOT NEGOTIABLE , already around 25% lower than the official price of the International Chemical Stock Exchange / ICIS .

<span style="color:red; font-weight:700; font-size:1.5em;">*</span> <span style="font-weight:700;">Possible additional discount for large quantity orders .</span>

packaging / transport

special for chemical transport (according to IATA / ADR / ECHA-REACH rules / int.l laws) .

certifications

C.O.A., MSDS, GMP, API, USP, EUP, ECHA-REACH, ORIGIN, etc… (originals will be delivered with good , and copies after confirmed order)

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