Additional information
Weight | 100 g |
---|---|
product name | Orotic acid, anhydrous, ACS |
synonyms | 2,6-Dihydroxypyrimidine-4-carboxylic acid, |
product origin | 100% made in European Union (according to USP, EUP, ECHA-REACH) |
purity grade | >99.99% (raw virgin matter, ultra-pure, sterilized) |
use | lab. / tech. / bio-research / intermediate / industrial |
product code | EA2294 |
C.A.S. number | 65-86-1 |
MDL | MFCD00006027 |
EINECS | 200-619-8 |
ID PubChem substance | 24897967 |
empirical formula | C5H4N2O4 (Hill Notation) |
formula weight | 156.10 |
melting point | >300 °C (lit.) |
solubility | slightly soluble in water |
stability | stable under normal conditions |
incompatible materials | bases, strong oxidizing agent, amines |
identification (FTIR) | conforms |
decomposition products | Nitrogen oxides (NOx); |
loss on drying | ≤1.5% (200 °C / constant weight) |
sensitivity & storage | ambient temperature |
assay | >99.99% |
appearance (color) | white |
form | powder |
applications | Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5?-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5?-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis. |
note (1) | <span style="font-weight:700; color:red;"> this product is for research use only, is not to be used for therapeutic ; not intended for animal or human or diagnostic or therapeutic use , and cannot be sold to patients.</span> |
note (2) | described price of the product is NOT NEGOTIABLE , already around 25% lower than the official price of the International Chemical Stock Exchange / ICIS . <span style="color:red; font-weight:700; font-size:1.5em;">*</span> <span style="font-weight:700;">Possible additional discount for large quantity orders .</span> |
packaging / transport | special for chemical transport (according to IATA / ADR / ECHA-REACH rules / int.l laws) . |
certifications | C.O.A., MSDS, GMP, API, USP, EUP, ECHA-REACH, ORIGIN, etc… (originals will be delivered with good , and copies after confirmed order) |
Reviews
There are no reviews yet.