O-Desmethyltramadol, ACS – 80456-81-1

 8720.00

SKU: 80456-81-1 Category:

Additional information

Weight 0.005 g
product name

O-Desmethyltramadol, ACS

synonyms

2-[(Dimethylamino)methyl]-1-(3-hydroxyphenyl)cyclohexanol,
O-Demethyl tramadol

product origin

100% made in European Union (according to USP, EUP, ECHA-REACH)

purity grade

>99.99% (raw virgin matter, ultra-pure, sterilized)

use

lab. / tech. / bio-research / enzyme
/ compound / industrial

product code

ESA304

C.A.S. number

80456-81-1

MDL

MFCD01311883

ID PubChem substance

329827665

empirical formula (Hill Notation)

C15H23NO2

formula weight

249.35

formulation

may be formulated in DMSO

sensitivity & storage

ambient temperature :
dry, dark and x 0 °C – 4 °C for short term (days to weeks),
or r dark o x -20 °C for long term (months to years)

solubility

soluble in DMSO

appearance (color)

white to off-white

form

powder

general description

O-Desmethyltramadol, an opioid, is an active metabolite of tramadol; the enzyme key for it is production is polymorphic cytochrome P450 isoenzyme 2D6 (CYP2D6).

biochem / physiol actions

O-Desmethyltramadol has a high affinity towards opioid receptors and is responsible for the analgesic effect of the μ-opioid receptor metabolite of tramadol O-Desmethyltramadol has been used for the pharmacokinetic studies of tramadol metabolites in goats .

applications

O-Desmethyltramadol may be used as an opioid to test its effect on the cytotoxic functionality of human natural killer cells.[3] It may also be used as an internal standard in gas chromatography-mass spectrometry (GC-MS) for quantification of tramadol based derivatives from human urine samples.

note (1)

<span style="font-weight:700; color:red;"> this product is for research use only, is not to be used for therapeutic ; not intended for animal or human or diagnostic or therapeutic use , and cannot be sold to patients.</span>

note (2)

described price of the product is NOT NEGOTIABLE , already around 25% lower than the official price of the International Chemical Stock Exchange / ICIS .

* Possible additional discount for large quantity orders .

packaging / transport

special for chemical transport (according to IATA / ADR / ECHA-REACH rules / int.l laws) .

certifications

C.O.A., MSDS, GMP, API, USP, EUP, ECHA-REACH, ORIGIN, etc… (originals will be delivered with good , and copies after confirmed order)

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