Folic acid,(glutamic acid-13C5), ACS, vitamin B 9, – CAS 59-30-3

Folic acid / vitamin B 9 has been used to induce acute kidney injury in mice ;
# as a supplement to cultivate MCF-7 breast cancer cells;
# to construct folate or TNF-related apoptosis-including ligand (TRAIL)-conjugated nanomicelles.
Enzyme cofactor essential for the synthesis, methylation, and repair of DNA; also supplements may reduce colorectal cancer risk; and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon′ transfer.
Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics)