Diamine Oxidase from porcine kidney, ACS – CAS 9001-53-0

Price f.o.b. for gr.1
 1096.00

CAS Number: 9001-53-0 Category:

Additional information

Weight 1 g
product name

Diamine Oxidase from porcine kidney, ACS

product origin

100% made in European Union (according to USP, EUP, ECHA-REACH)

purity grade

>99.99% (raw virgin matter, ultra-pure, concentrated, sterilized)

use

lab. / tech. / bio-research

product code

ES6787A

C.A.S. number

9001-53-0

MDL

MFCD00130946

EINECS

232-613-6

molecular weight

170 kDa

specific activity

≥0.05 unit/mg solid

foreign activity

monoamine oxidase (benzylamine substrate) ≤1%

solubility

100 mM sodium phosphate buffer, pH 7.2: soluble 10 mg/mL

stability

the product is chemically stable under standard conditions

unit definition

one unit will oxidize 1.0 μmole of putrescine per hr at pH 7.2 at 37 °C

storage temperature

<-20 °C

assay

>99.99% to <102.00%

appearance (color)

white

form

powder

description

Diamine oxidase from porcine kidney is a homodimer consisting of two equal subunits with a molecular weight of 87 kDa each; each subunit contains one molecule of pyridoxal phosphate and one atom of copper ; the molecular mass of the enzyme is found to be 170 kDa : the enzyme is a glycoprotein containing 5% hexose, 3.3% glucosamine, 2.6% N-acetylglucosamine, and 0.25% N-acetylneuraminic acid; the enzyme exhibits a high affinity for concanavalin A ; optimum pH with cadverine and histamine as substrates is found to be 6.3 – 7.4
Diamine Oxidase from porcine kidney has been used in the construction of histamine biosensor; Diamine oxidase from porcine kidney has been used in a study to investigate a luminescence-based test for determining ornithine decarboxylase activity; Diamine oxidase from porcine kidney has also been used in a study to investigate N-linked oligosaccharide structures in diamine oxidase

note (1)

Diamine Oxidase catalyzes the oxidation of monoamines, diamines, and histamine to aldehydes, ammonia, and hydrogen peroxide; the enzyme is classified as a copper amine oxidase and it is a key enzyme in nitrogen metabolism ; Diamine oxidase is inhibited by diethyldithiocarbamate, phenylhydrazine, semicarbazide, cyanide, isonicotinic acid hydrazide

note (2)

this product is for research use only, is not to be used for therapeutic ; not intended for animal or human or diagnostic or therapeutic use , and cannot be sold to patients.

note (3)

described price of the product is NOT NEGOTIABLE , already around 25% lower than the official price of the International Chemical Stock Exchange / ICIS .

* Possible additional discount for large quantity orders .

packaging / transport

special for chemical transport (according to IATA / ADR / ECHA-REACH rules / int.l laws) .

certifications

C.O.A., MSDS, GMP, API, USP, EUP, ECHA-REACH, ORIGIN, etc… (originals will be delivered with good , and copies after confirmed order)

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