Additional information
Weight | 1 g |
---|---|
product name | Diamine Oxidase from porcine kidney, ACS |
product origin | 100% made in European Union (according to USP, EUP, ECHA-REACH) |
purity grade | >99.99% (raw virgin matter, ultra-pure, concentrated, sterilized) |
use | lab. / tech. / bio-research |
product code | ES6787A |
C.A.S. number | 9001-53-0 |
MDL | MFCD00130946 |
EINECS | 232-613-6 |
molecular weight | 170 kDa |
specific activity | ≥0.05 unit/mg solid |
foreign activity | monoamine oxidase (benzylamine substrate) ≤1% |
solubility | 100 mM sodium phosphate buffer, pH 7.2: soluble 10 mg/mL |
stability | the product is chemically stable under standard conditions |
unit definition | one unit will oxidize 1.0 μmole of putrescine per hr at pH 7.2 at 37 °C |
storage temperature | <-20 °C |
assay | >99.99% to <102.00% |
appearance (color) | white |
form | powder |
description | Diamine oxidase from porcine kidney is a homodimer consisting of two equal subunits with a molecular weight of 87 kDa each; each subunit contains one molecule of pyridoxal phosphate and one atom of copper ; the molecular mass of the enzyme is found to be 170 kDa : the enzyme is a glycoprotein containing 5% hexose, 3.3% glucosamine, 2.6% N-acetylglucosamine, and 0.25% N-acetylneuraminic acid; the enzyme exhibits a high affinity for concanavalin A ; optimum pH with cadverine and histamine as substrates is found to be 6.3 – 7.4 |
note (1) | Diamine Oxidase catalyzes the oxidation of monoamines, diamines, and histamine to aldehydes, ammonia, and hydrogen peroxide; the enzyme is classified as a copper amine oxidase and it is a key enzyme in nitrogen metabolism ; Diamine oxidase is inhibited by diethyldithiocarbamate, phenylhydrazine, semicarbazide, cyanide, isonicotinic acid hydrazide |
note (2) | this product is for research use only, is not to be used for therapeutic ; not intended for animal or human or diagnostic or therapeutic use , and cannot be sold to patients. |
note (3) | described price of the product is NOT NEGOTIABLE , already around 25% lower than the official price of the International Chemical Stock Exchange / ICIS . * Possible additional discount for large quantity orders . |
packaging / transport | special for chemical transport (according to IATA / ADR / ECHA-REACH rules / int.l laws) . |
certifications | C.O.A., MSDS, GMP, API, USP, EUP, ECHA-REACH, ORIGIN, etc… (originals will be delivered with good , and copies after confirmed order) |
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